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Chronic Liver disease (CLD) is a condition characterized by a gradual loss of kidney function over time. CLD can be asymptomatic in early stage.Common symptoms of CLD includes easy fatigability or tiredness, reduced appetite, Jaundice, weight loss, swelling over leg or abdomen, muscle cramps/ pain etc.
Common cause of chronic liver disease are Viral Infection (Hepatitis), Alcohol abuse.
Hepatitis is an inflammation of the liver. It can be caused by drugs, alcohol use, infectious agents (e.g. virus, bacteria etc.) or certain medical conditions. But in most cases, it's caused by a virus. This is known as viral hepatitis, and the most common forms are hepatitis A, B, C and E.
Diagnosis-Hepatitis and its subtype can be determined by blood investigations in laboratory.
Complications- Commonest complications of chronic hepatitis is cirrhosis (see below). Another complication liver cancer which is more common with chronic viral hepatitis B or C. So people with chronic hepatitis B or C need monitoring even if they feel healthy. Blood tests can detect proteins that suggest the presence of liver cancer. Ultrasounds, CT scans, and MRIs can reveal abnormality in the liver.
Cirrhosis is a serious disease that occurs when healthy cells in the liver are damaged and replaced by scar tissue, usually as a result of alcohol abuse or chronic hepatitis. As liver cells give way to tough scar tissue, the organ loses its ability to function properly. Cirrhosis cannot be reversed or cured except, in some cases, through a liver transplant.
Radiologic imaging like ultrasonography, CT scan, MRI can diagnose cirrhosis. Liver biopsy is essential to determine severity and microscopic subtype of cirrhosis.